TABLE OF CONTENTS
Copyright and ACKNOWLEDGEMENTS
CHAPTER 1. THE NUTS AND BOLTS OF BONE MARROW TRANSPLANTS
11. What is Bone Marrow?
11. Why a Transplant?
12. Types of Transplant
13. Preparing for the Transplant
13. Bone Marrow Harvest
14. Preparative Regimen
15. The Transplant
15. Engraftment
16. What a Patient Feels During the Transplant
17. Handling Emotional Stress
18. Leaving the Hospital
18. Life after Transplant
19. Is It Worth It?
CHAPTER 2. SOME FUNDAMENTALS ABOUT BLOOD CELLS
22. Blood Cell Production
CHAPTER 3. AUTOLOGOUS BONE MARROW TRANSPLANTS
25. Who Is a Candidate for an Autologous BMT?
26. Hodgkin's and Non-Hodgkin's Lymphomas
27. Leukemia
28. Breast Cancer
29. Childhood Neuroblastoma
30. Other Diseases
30. Purging Bone Marrow
31. Post-Recovery
31. Georgia Comfort
CHAPTER 4. ALLOGENEIC BONE MARROW TRANSPLANTS
34. The HLA System
37. HLA-Matching
37. HLA-Typing Test
38. Matched Related Donors
38. Acute Myelogenous Leukemia (AML)
39. Acute Lymphocytic Leukemia (ALL)
39. Chronic Myelogenous Leukemia (CML)
39. Hodgkin's and Non-Hodgkin's Lymphomas
40. Aplastic Anemia
40. Mis-Matched BMTS
41. Unrelated Donor Transplants
42. Searching for an Unrelated Donor
43. Being a Donor
44. Laura Wise
CHAPTER 5. PERIPHERAL STEM CELL TRANSPLANTS
47. Stem Cells
48. Peripheral Stem Cell Harvest
49. Reasons for PSCHS
49. Pros and Cons of PSCHS
50. Thelda DeLanghe
CHAPTER 6. EMOTIONAL AND PSYCHOLOGICAL CONSIDERATIONS
53. Coping with the News
54. Getting Information
54. Setting Goals
55. Loss of Control
57. Isolation
58. Physical Discomfort
59. Psychiatric Help
59. Being There for the Patient
61. Getting Back to Normal
63. And Many Months Beyond
64. Poem UnreadyHeroes
CHAPTER 7. WHEN YOUR CHILD NEEDS A BONE MARROW TRANSPLANT
67. Deciding on a BMT
68. Getting Information
70. Preparing for the Transplant
72. Siblings' Concerns
73. The Sibling Donor
73. Waiting for the Transplant
74. Life During Transplant
77. Going Home
CHAPTER 8. INFECTIONS
82. Fighting Infection - The Immune System
82. Lymphocytes
83. Other Leukocytes
83. Bacterial Infections
85. Fungal Infections
86. Viral Infections
86. Herpes Simplex
87. Cytomegalovirus
87. Varicella Zoster Virus
88. Other Viruses
88. Protozoa
90. Don't Take Chances
CHAPTER 9. GRAFT-VERSUS-HOST DISEASE
91. T-cells
92. GVHD
92. Acute GVHD
93. Prevention & Treatment of Acute GVHD Treatment of Acute GVHD
94. T-cell Depletion
95. Chronic GVHD
96. Treatment of Chronic GVHD
97. Long-Term Concerns
97. Coping with the Stress of GVHD
99. Susan Mitchell
CHAPTER 10. LIVER COMPLICATIONS
102. During the First Three Months after a BMT
102. Veno-Occlusive Disease
104. Acute GVHD of the Liver
104. Bloodstream Infections
104. Fungal Liver Disease
105. Drug-Induced Liver Injury
106. Viral Hepatitis
106. Biliary Disease
106. After the Third Month Post-Transplant
107. Chronic GVHD of the Liver
107. Chronic Viral Hepatitis
107. Fungal Liver Disease
CHAPTER 11. INFERTILITY
110. Steps to Pregnancy
111. Sperm Production
112. Chemotherapy 112. Chemotherapy & Radiation Radiation
114. Medically Assisted Reproduction
114. Artificial Insemination
116. In-vitro Fertilization
118. Choosing a Program
119. Emotional Considerations
119. The Adoption Option
119. Agency-Assisted Adoption
120. Private Adoption
121. Cost
121. Emotional Considerations
CHAPTER 12. INSURANCE AND BONE MARROW TRANSPLANTS
124. What Types of Insurance Are Available?
124. Private Insurance
125. Self-Insured
125. HMOs (Health Maintenance Organizations)
126. Government Programs
126. Other Plans
127. Is Your Health Insurance Adequate?
128. When Insurance Says No
129. What's the Problem?
129. Experimental/Investigative
130. Not Medically Necessary
131. Not Eligible
131. Usual and Customary
133. Going to Court
133. BMT Newsletter 1991 Insurance Survey
134. Gail Pitman
APPENDIX A: UNDERSTANDING BLOOD TESTS
APPENDIX B: RESOURCES
APPENDIX C: GLOSSARY OF TERMS
INDEX