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Issue #48

Learning about Cancer the Electronic Way
Advances in Research Reported by Hematologists
Survivor Makes Comeback as Mystery Writer
Drug Fights Myelogenous Leukemia


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Breast Cancer Research Study Results Discredited

A researcher at the University of Witwatersrand Medical School in Johannesburg, South Africa, was fired for scientific misconduct after independent auditors found serious irregularities in a study he conducted about the benefits of high-dose chemotherapy followed by bone marrow transplantation in women with high risk breast cancer.

Dr. Werner Bezwoda, PhD, the author of the study, presented his results at a meeting of the American Society of Clinical Oncology in May 1999. His study found a significant survival benefit for women treated with high-dose chemotherapy and an autologous bone marrow transplant versus standard treatment. A team of American investigators, who visited South Africa to confirm Bezwoda’s results before commencing a clinical trial using the same protocol in the United States, found several serious improprieties and breaches of acceptable research practice in the study. As a result, the University has officially rescinded the study.




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