Imatinib
Trade Names:
Gleevec®
Possible Uses:
CML (chronic myelogenous leukemia), Philadelphia + ALL, Gastrointestinal stromal tumors (GIST)
Special Notes:
take with food and a full glass of water to decrease nausea and stomach upset
Drug Interactions:
possible interactions with warfarin, phenytoin, carbamazepine, rifampin, phenobarbital, ketoconazole, itraconazole, erythromycin, clarithromycin, and St. John's wort
Possible Side Effects:
nausea, fluid retention (especially around eyes and ankles), weight gain, diarrhea, neutropenia, thrombocytopenia, may alter liver function testing, skin rashes, which can be severe Last updated on 02/01/2010









